Intense Replenishing Serum product
Woman rubbing Intense Replenishing Serum product on cheek

Intense Replenishing Serum

$28
4.8
Rated 4.8 out of 5 stars
179 Reviews
Get that natural, dewy glow all while fighting visible signs of aging with this rich and silky serum.
Address the real world factors we face each day:
Pollution
Light
Climate
Irritants
Prime, soothe, and protect your skin with our award-winning Intense Replenishing Serum. Made for daily moisture and luminosity, this multi-purpose serum plumps, smooths, and protects your skin against free radical damage. Formulated with antioxidant Lipochroman®, the strongest antioxidant on the market, you’ll defend against pollution particles and reduce the appearance of fine lines and dark spots. Paired with replenishing glycolipids and calming vitamins E and F, this superstar serum instantly restores silky texture. Plus, it gives your skin that beautiful, dewy look you’re bound to love.
All skin types.
Plumping skin appearance
Protecting against pollution and climate
Creating a natural, dewy glow
Boosting hydration
Cyclopentasiloxane, Ethylhexyl Cocoate, Dimethiconol, Phenoxyethanol, Dimethylmethoxy Chromanyl Palmitate, Glyceryl Linoleate, Glyceryl Oleate, Dimethylmethoxy Chromanol, Tocopheryl Acetate, Glyceryl Palmitate, Glycolipids, Water (Water/Eau), Glyceryl Linolenate, Glyceryl Stearate, Lecithin, Tocopherol, Glycine Soja (Soybean) Oil, Polylysine.
After cleansing, apply to face and neck. Use AM and PM. Always finish with SPF in the morning.
Can be used as a makeup primer or on hair for a lightweight, long-lasting shine.

Once you're done with Intense Replenishing Serum, be sure to properly clean it out so there's no product remaining inside. Then fill out a form for your free shipping label and ship it out to get recycled!

Click here to start recycling.

The Intense Replenishing Serum bottle is 100% recyclable.
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Real Science. Real Results.
Clinical test results after 2 weeks*
  • 100%
    showed clinically measured improvement in fine lines
  • 100%
    showed clinically measured improvement in skin radiance
  • 100%
    showed clinically measured improvement in transepidermal water loss
Before
After 2 weeks
*Based on Instrumental Testing with 33 subjects, ages 30-60, who applied Intense Replenishing Serum twice a day during an four-week period.
Real Science. Real Results.
Consumer perception results after 4 weeks*
  • 100%
    agreed their skin feels more hydrated
  • 100%
    agreed their skin looked intensely replenished
  • 97%
    agreed their skin looked plumper
Before
After 2 weeks
*Based on a Consumer Perception Survey with 33 subjects, ages 30-60, who applied Intense Replenishing Serum twice a day over a four-week period.
Female-Founded Family-Run Dermatologist-Formulated Clinically Tested 100% Vegan Cruelty-Free
Key Ingredients.
Antioxidant Lipochroman™
A powerful antioxidant that protects skin from free radical damage to improve the appearance of fine lines, wrinkles, and dark spots.
Glycolipids
Replenish natural moisture to provide instant radiance and keep skin well-hydrated.
Chromabright™
A highly effective brightening ingredient inspired by Vitamin E that visibly brightens uneven skin tone and protects skin from free radical damage and HEV (blue light).
Vitamins E & F
Calm skin and promote a healthy skin barrier while providing antioxidant protection.

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Reviews

4.8
Rated 4.8 out of 5 stars
Based on 179 reviews
Total 5 star reviews: 157 Total 4 star reviews: 17 Total 3 star reviews: 3 Total 2 star reviews: 2 Total 1 star reviews: 0
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179 reviews
  • AD
    Amy D.
    Verified Buyer
    I recommend this product
    Age Range 45-54
    What is your skin type? Normal
    What are your skin concerns? Dry / Dehydrated, Fine Lines / Wrinkles, Under Eye Puffiness / Dark Circles
    Rated 5 out of 5 stars
    1 week ago
    A Game-Changer for Dehydrated, Stressed Skin!

    I’ve tried countless serums over the years, but Dr. Loretta’s Intense Replenishing Serum has genuinely impressed me. From the first use, my skin felt noticeably more hydrated, soothed, and supple. It has a silky texture that glides on effortlessly and absorbs beautifully—no stickiness, no pilling, just pure comfort.

    What really sets this serum apart is how nourishing yet lightweight it is. Packed with antioxidants and lipids, it targets dryness, dullness, and environmental stressors without overwhelming the skin. It’s become a must-have in both my morning and evening routines, especially when my skin feels tight or reactive.

    After a few weeks of consistent use, I’ve noticed a visible improvement in my skin’s tone and resilience. It looks healthier, more radiant, and just feels stronger overall. I also love that it’s fragrance-free and formulated by a dermatologist, so it feels both luxurious and skin-smart.

    If you’re dealing with dryness, irritation, or want to boost your barrier health, this serum is a holy grail. Highly, highly recommend!

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  • KP
    Kimberly P.
    Verified Buyer
    I recommend this product
    Age Range 55-64
    What is your skin type? Combination
    What are your skin concerns? Dullness, Sensitive Skin, Fine Lines / Wrinkles, Under Eye Puffiness / Dark Circles, Adult Acne
    Rated 5 out of 5 stars
    3 weeks ago
    Great serum

    Dr. Loretta's products saved my skin. If I have blemishes it is as if the serum helps correct them overnight. Now I rarely get any blemishes and my skin is so healthy. Love the products???

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  • SL
    Sarah L.
    Verified Buyer
    I recommend this product
    Age Range 25-34
    What is your skin type? Dry
    What are your skin concerns? Dry / Dehydrated, Sensitive Skin
    What did you love about the product? Improved my skin concerns, Sensory experience
    Rated 5 out of 5 stars
    3 weeks ago
    Just what I needed

    It’s been awhile since I have used this serum and my skin was so dry no matter what I used or did, until I reintroduced this serum back into my routine and goodness gracious it provided so much relief to my dry skin!

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  • LR
    Loree R.
    Verified Buyer
    I recommend this product
    Age Range Over 65
    What is your skin type? Normal
    What are your skin concerns? Dry / Dehydrated, Fine Lines / Wrinkles, Loss Of Firmness, Texture
    What did you love about the product? Visible results, Sensory experience
    Rated 5 out of 5 stars
    1 month ago
    Replenishing serum

    Leaves a velvet blurring effect .LOVE it …

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  • PB
    Pamela B.
    Verified Buyer
    I recommend this product
    Age Range Over 65
    What is your skin type? Normal
    What are your skin concerns? Sensitive Skin, Under Eye Puffiness / Dark Circles, Dark Spots / Hyperpigmentation
    Rated 5 out of 5 stars
    1 month ago
    Best serum out there!

    I'm the same age as Dr. Loretta and have been serious about skin care since I turned 30. Through the years I was a Sephora junkie and became allergic to fragrances. I started using Dr Loretta's products shortly after they came out and they work wonderfully and I have had zero problems. I honestly think I look ten years younger than I am! Thanks Dr. Loretta!

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